Wetenschap
  • Title: Diagnosing Sport-Related Flow Limitations in the Iliac Arteries Using Near-Infrared Spectroscopy
  • Open Access: Ja
  • Language: English
  • Year: 2022
  • DOI/URL: https://doi.org/10.3390/jcm11247462
  • Publication Date: 16-12-2022
  • Journal: MDPI - Journal of Clinical Medicine
  • Authors:

    Hooff van, M. ORCID iD

    Arnold, J. ORCID iD

    Meijer, E. ORCID iD

    Schreuder, P. ORCID iD

    Regis, M. ORCID iD

    Xu, L. ORCID iD

    Scheltinga, M. ORCID iD

    Savelberg, H. ORCID iD

    Schep, G. ORCID iD

  • Pubmed ID: 36556078

Background: A flow limitation in the iliac arteries (FLIA) in endurance athletes is notoriously difficult to diagnose with the currently available diagnostic tools. At present, a commonly used diagnostic measure is a decrease in ankle brachial index with flex hips (ABIFlexed) following a maximal effort exercise test. Near-infrared spectroscopy (NIRS) is a non-invasive technique that measures skeletal muscle oxygenation as reflected by the balance of O2 delivery from microvascular blood flow and O2 uptake by metabolic activity. Therefore, NIRS potentially serves as a novel technique for diagnosing FLIA. The purpose of this study is to compare the diagnostic accuracy of NIRS-derived absolute, amplitude, and kinetic variables in legs during and after a maximal exercise test with ABIFlexed.

Methods: ABIFlexed and NIRS were studied in 33 healthy subjects and 201 patients with FLIA diagnosed with echo-Doppler.

Results: After maximal exercise, NIRS kinetic variables, such as the half value time and mean response time, resulted in a range of 0.921 to 0.939 AUC for the diagnosis of FLIA when combined with ABIFlexed. Conversely, ABIFlexed measurements alone conferred significantly worse test characteristics (AUC 0.717, p < 0.001).

Conclusion: NIRS may serve as a diagnostic adjunct in patients with possible FLIA.

 

 

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