Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes

01 april 2019 Objective: High-performance athletes can develop symptomatic arterial flow restriction during exercise caused by endofibrosis. The pathogenesis is poorly understood; however, coagulation enzymes, such as tissue factor (TF) and coagulation factor Xa,...

The biology of external iliac artery endofibosis: What can we learn from this disease to help us treat other fibroproliferative arteriopathies?

01 april 2019 Arterial endofibrosis is a vascular disease that typically affects the external iliac artery in young patients who undergo extreme exercise, mainly bicyclists.1 The diagnosis is indirectly suspected when these extreme athletes undergo ankle-brachial...

Pedal power measurement as a diagnostic tool for functional vascular problems

01 januari 2019 Background: Cyclists with flow limitations in the iliac arteries complain of pain and loss of power. To investigate whether pedal power measurement has added value in diagnosing the underlying cause of flow limitations in the iliac arteries, we...